Product name: |
LC3A (5G10) Mouse mAb |
Reactivity: |
Human, Rat, Mouse |
Alternative Names: |
ATG8E, MAP1LC3A,autophage-related protein LC3A |
Source: |
Mouse |
Dilutions: |
WB 1:1,000-2,000 IHC 1:100-200 |
Immunogen: |
Synthetic Peptide |
Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
Clonality: |
Monoclonal |
Isotype: |
IgG1 |
Concentration: |
1mg/mL |
Observed Band: |
14,16kDa |
GeneID: |
84557 |
Human Swiss-Prot No: |
Q9H492 |
Cellular localization: |
Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, Membrane, Microtubule |
Background: |
Three human LC3 isoforms (LC3A, LC3B, and LC3C) undergo post-translational modifications during autophagy. Cleavage of LC3 at the carboxy terminus immediately following synthesis yields the cytosolic LC3-I form. |