| Product name: |
Bax (6F11) Mouse mAb |
| Reactivity: |
Human, Rat, Mouse |
| Alternative Names: |
Apoptosis regulator bax, BAXA, BCL2 associated X protein |
| Source: |
Mouse |
| Dilutions: |
WB 1:1,000-2,000 IHC 1:100-200 |
| Immunogen: |
Synthetic Peptide |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality: |
Monoclonal |
| Isotype: |
IgG1 |
| Concentration: |
1mg/mL |
| Observed Band: |
20kDa |
| GeneID: |
581 |
| Human Swiss-Prot No: |
Q07812 |
| Cellular localization: |
Cytoplasm, Membrane, Mitochondrion |
| Background: |
Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. |
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