| Product name: |
Caspase-3 (4B8) Mouse mAb |
| Reactivity: |
Human, Rat, Mouse |
| Alternative Names: |
APOPAIN antibody, CASP 3 antibody, CPP32 antibody, Cysterine protease CPP32 antibody |
| Source: |
Mouse |
| Dilutions: |
IHC 1:100-200 |
| Immunogen: |
Synthetic Peptide |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality: |
Monoclonal |
| Isotype: |
IgG1 |
| Concentration: |
1mg/mL |
| Observed Band: |
17,32kDa |
| GeneID: |
836 |
| Human Swiss-Prot No: |
P42574 |
| Cellular localization: |
Cytoplasm |
| Background: |
Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP). |
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