| Product name: |
Galectin-3 Mouse mAb |
| Reactivity: |
Human, Mouse |
| Alternative Names: |
35 kDa lectin, CBP 35, CBP35, Gal 3, GAL3, Galactose specific lectin 3, Galactoside binding protein, GALBP, Galectin 3, Galectin-3, GALIG, IgE binding protein, L 31, Laminin binding protein, Lectin L 29, LGALS2, LGALS3, Mac 2 antigen, MAC2 |
| Source: |
Mouse |
| Dilutions: |
WB 1:1,000-2,000 IHC 1:100-200 ELISA 10,000-50,000 |
| Immunogen: |
Protein |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality: |
Monoclonal |
| Isotype: |
IgG1 |
| Concentration: |
1mg/mL |
| Observed Band: |
26kDa |
| GeneID: |
3958 |
| Human Swiss-Prot No: |
P17931 |
| Cellular localization: |
Cytoplasm, Nucleus, Secreted, Spliceosome |
| Background: |
Galectin 3 is one of the more extensively studied members of this family and is a 30 kDa protein. Due to a C-terminal carbohydrate binding site, Galectin 3 is capable of binding IgE and mammalian cell surfaces only when homodimerized or homooligomerized. Galectin 3 is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. |
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