Product name: | Survivin Mouse mAb |
Reactivity: | Human, Rat |
Source: | Mouse |
Dilutions: | WB 1:1,000-2,000 IHC 1:200-500 |
Immunogen: | Recombinant Protein |
Storage: | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
Clonality: | Monoclonal |
Isotype: | IgG1 |
Concentration: | 1mg/mL |
Observed Band: | 16kDa |
GeneID: | 332 |
Human Swiss-Prot No: | O15392 |
Cellular localization: | Cytoplasm. Nucleus. Chromosome |
Background: | Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene. Survivin is a member of the inhibitor of apoptosis (IAP) family. The survivin protein functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. |