| Product name: |
Caspase 9 Mouse mAb |
| Reactivity: |
Human, Rat, Mouse |
| Alternative Names: |
APAF 3 antibody, Apoptosis related cysteine peptidase antibody, Apoptotic protease-activating factor 3 antibody, CASP 9 antibody |
| Source: |
Mouse |
| Dilutions: |
WB 1:1,000-5,000 IP 1:200 IF 1:100-200 |
| Immunogen: |
Synthetic Peptide |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality: |
Monoclonal |
| Isotype: |
IgG1 |
| Concentration: |
1mg/mL |
| Observed Band: |
47（51）kDa |
| GeneID: |
842 |
| Human Swiss-Prot No: |
P55211 |
| Cellular localization: |
Cytosol,Mitochondrion,Nucleus |
| Background: |
Caspase-9 is an initiator caspase, encoded by the CASP9 gene.Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). |
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