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CD5 Mouse mAb
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EM1071
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50 µL $148.00
100 µL $248.00
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Overview

Product name: CD5 Mouse mAb
Reactivity: Human, Rat, Mouse
Alternative Names: CD5 molecule, LEU1, Lymphocyte antigen T1/Leu 1, T1
Source: Mouse
Dilutions: IHC 1:100-200
Immunogen: Synthetic Peptide
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
GeneID: 921
Human Swiss-Prot No: P06127
Cellular localization: Membrane
Background: CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins.