Product name: | WIPI2 Rabbit pAb |
Reactivity: | Human, Mouse, Rat |
Alternative Names: | ATG21, CGI50 |
Source: | Rabbit |
Dilutions: | IHC 1:100-200 |
Immunogen: | Recombinant Protein |
Storage: | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1mg/mL |
Observed Band: | 49kDa |
GeneID: | 26100 |
Human Swiss-Prot No: | Q9Y4P8 |
Cellular localization: | Membrane |
Background: | WIPI2 is the mammalian homolog of Atg18, not Atg21, along with the closely related protein, WIPI1. WD40 repeat proteins regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids. |