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ATG4a Rabbit pAb
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EA347
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50 µL $148.00
100 µL $248.00
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Overview

Product name: ATG4a Rabbit pAb
Reactivity: Human, Mouse, Rat
Alternative Names: Apg4a, Atg4al, Autl2,Cysteine protease ATG4A antibody
Source: Rabbit
Dilutions: IHC 1:100-200
Immunogen: Recombinant Protein
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Polyclonal
Isotype: IgG
Concentration: 1mg/mL
Observed Band: 45kDa
GeneID: 115201
Human Swiss-Prot No: Q8WYN0
Cellular localization: Cytoplasm
Background: Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Control of autophagy was largely discovered in yeast and involves proteins encoded by a set of autophagy-related genes (Atg). Formation of autophagic vesicles requires a pair of essential ubiquitin-like conjugation systems, Atg12-Atg5 and Atg8-phosphatidylethanolamine (Atg8-PE), which are widely conserved in eukaryotes. Numerous mammalian counterparts to yeast Atg proteins have been described, including three Atg8 proteins (GATE-16, GABARAP, and LC3) and four Atg4 homologs (Atg4A/autophagin-2, Atg4B/autophagin-1, Atg4C/autophagin-3, and Atg4D/autophagin-4).