| Product name: |
Acrosin rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
ACR; ACRS; Acrosin |
| Source: |
Rabbit |
| Dilutions: |
IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: |
Synthesized peptide derived from Acrosin . at AA range: 40-120 |
| Storage: |
-20°C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
45kD |
| GeneID: |
49 |
| Human Swiss-Prot No: |
P10323 |
| Cellular localization: |
acrosomal vesicle,extracellular region,nucleus,Golgi-associated vesicle,acrosomal matrix,protein complex, |
| Background: |
Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids. [provided by RefSeq, Jul 2008], |
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