| Product name: |
ERK1/2 (1H4) Mouse mAb |
| Reactivity: |
Human, Rat, Mouse |
| Alternative Names: |
MAPK, Mitogen-activated protein Kinase, PRKM2,MK01 |
| Source: |
Mouse |
| Dilutions: |
WB 1:1,000-2,000 IHC 1:100-200 |
| Immunogen: |
Synthetic Peptide |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality: |
Monoclonal |
| Isotype: |
IgG1 |
| Concentration: |
1mg/mL |
| Observed Band: |
44,42kDa |
| GeneID: |
5594/5595 |
| Human Swiss-Prot No: |
P27361/P28482 |
| Cellular localization: |
Nucleus |
| Background: |
Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer. |
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