Product name: | ERK1 (5E9) Mouse mAb |
Reactivity: | Human, Rat, Mouse |
Alternative Names: | MAPK, Mitogen-activated protein Kinase, PRKM2,MK01 |
Source: | Mouse |
Dilutions: | IHC 1:100-200 |
Immunogen: | Recombinant Protein |
Storage: | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
Clonality: | Monoclonal |
Isotype: | IgG1 |
Concentration: | 1mg/mL |
Observed Band: | 44kDa |
GeneID: | 5594 |
Human Swiss-Prot No: | P27361 |
Cellular localization: | Nucleus |
Background: | Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer. |