| Product name: |
CHOP (2B1) Mouse mAb |
| Reactivity: |
Human, Rat, Mouse |
| Alternative Names: |
GADD153, DDIT3,MGC4154 |
| Source: |
Mouse |
| Dilutions: |
WB 1:1,000-2,000 IHC 1:100-200 |
| Immunogen: |
Synthetic Peptide |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Clonality: |
Monoclonal |
| Isotype: |
IgG1 |
| Concentration: |
1mg/mL |
| Observed Band: |
27kDa |
| GeneID: |
1649 |
| Human Swiss-Prot No: |
P35638 |
| Cellular localization: |
Nucleus |
| Background: |
CHOP was identified as a C/EBP-homologous protein that inhibits C/EBP and LAP in a dominant-negative manner. CHOP expression is induced by certain cellular stresses including starvation and the induced CHOP suppresses cell cycle progression from G1 to S phase. |
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