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CD20 Mouse mAb
EM1048
Specification: Price:
50 µl $148.00
100 µl $248.00

Overview

Product name: CD20 Mouse mAb
Species reactivity: Human, Rat, Mouse
Reactivity: Human, Rat, Mouse
Alternative Names: B lymphocyte antigen CD20, B1, Bp35, LEU 16, MS4A1, MS4A1,MS4A2, S7
Source: Mouse
Applications : IHC
Species: Human
Recommended dilutions: IHC 1:200
Immunogen: Synthetic Peptide
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/ml
Observed band: 35-37kDa
GeneID(Human): 931
Human Swiss-Prot No.: P11836
Cellular localization: Membrane
Background: CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca2+ channel subunit.

Precision

Intra-assay Precision (Precision within an assay):CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Inter-assay Precision (Precision between assays):CV%<10%

Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.