|Product name:||AMACR/P504S Mouse mAb|
|Species reactivity:||Human, Rat, Mouse|
|Reactivity:||Human, Rat, Mouse|
|Alternative Names:||Alpha-Methylacyl Coenzyme A Racemase ;RACE; 2-methylacyl-CoA racemase|
|Applications :||WB, IHC|
|Recommended dilutions:||WB 1:1,000 IHC 1:200|
|Storage:||PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.|
|Human Swiss-Prot No.:||Q9UHK6|
|Cellular localization:||Peroxisome. Mitochondrion|
|Background:||AMACR has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.|
Intra-assay Precision (Precision within an assay)：CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)：CV%<10%
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.