|Product name:||ErbB-2/HER-2 Mouse mAb|
|Species reactivity:||Human, Rat, Mouse|
|Reactivity:||Human, Rat, Mouse|
|Alternative Names:||CD340, HER 2/neu, HER2, MLN 19, MLN19, NEU, NGL, p185, p185erbB2, Proto oncogene c ErbB 2, Proto oncogene Neu, TKR1|
|Applications :||WB, IHC|
|Recommended dilutions:||WB 1:2,000-4,000 IHC 1:200|
|Storage:||PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.|
|Human Swiss-Prot No.:||P04626|
|Cellular localization:||Cytoplasm. Nucleus and Cell membrane|
|Background:||ErbB 2 is a receptor tyrosine kinase of the ErbB 2 family. It is closely related instructure to the epidermal growth factor receptor. ErbB 2 oncoprotein is detectable in a proportion of breast and other adenocarconomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis.|
Intra-assay Precision (Precision within an assay)：CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)：CV%<10%
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.