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Bcl-2 Mouse mAb
EM1041
Specification: Price:
50 µl $148.00
100 µl $248.00

Overview

Product name: Bcl-2 Mouse mAb
Species reactivity: Human, Rat, Mouse
Reactivity: Human, Rat, Mouse
Alternative Names: B-Cell Leukemia/Lymphoma 2 ;B-Cell CLL/Lymphoma 2
Source: Mouse
Applications : WB, IHC, IF
Species: Human
Recommended dilutions: WB 1:1,000-2,000 IHC 1:200 IF 1:100-200
Immunogen: Synthetic Peptide
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/ml
Observed band: 26kDa
GeneID(Human): 596
Human Swiss-Prot No.: P10415
Cellular localization: Mitochondrion outer membrane,Nucleus membrane,Endoplasmic reticulum membrane
Background: BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability.

Precision

Intra-assay Precision (Precision within an assay):CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Inter-assay Precision (Precision between assays):CV%<10%

Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.