IRS-1 (phospho Tyr896) Rabbit pAb
Specification: Price:
50 µl $148.00
100 µl $248.00


Product name: IRS-1 (phospho Tyr896) Rabbit pAb
Reactivity: Human,Mouse,Rat
Alternative Names: IRS1; Insulin receptor substrate 1; IRS-1
Source: Rabbit
Applications: WB, ELISA
Immunogen: Synthesized peptide derived from human IRS-1 around the phosphorylation site of Y896.
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Polyclonal
Concentration: 1mg/ml
Observed band: 180kDa
GeneID(Human): 3667
Background: Insulin receptor substrate 1 (IRS1) was the first cloned and characterized member of the IRS family which are involved in insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) signaling. IRS1 is phosphorylated by insulin receptor tyrosine kinase and is involved in various cellular processes including DNA repair fidelity, transcriptional activity, and cell growth can support tumor development and progression. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.