Current Position:HomeProductsPrimary AntibodiesMonoclonal Antibodies

P63-α (3F11) Mouse mAb

Catalog No. : EM1404

Specification Price
50µl $148
100µl $248

Overview

Product name: P63-α (3F11) Mouse mAb
Source: Mouse
Applications: WB, IHC
Species reactivity: Human,Rat,Mouse
Recommended dilutions: WB 1:1,000-2,000   IHC:1;100-1:200
Immunogen: Synthetic Peptide
Specificity: Human
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/ml
Observed band: 50-80kDa
GeneID(Human): 8626
Human Swiss-Prot No.: Q9H3D4
Cellular localization: Nucleus
Alternative Names: N/A
Background: p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors . Research investigators frequently observe amplification of the p63 gene in squamous cell carcinomas of the lung, head and neck . The p63 gene contains an alternative transcription initiation site that yields a 40 kDa δNp63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the α, β, and γ isoforms .
  • Western blot analysis of 1) A431 Cell Lysate, 2) 3T3 Cell Lysate , 3) PC-12 Cell Lysate using P63-α(EM1404)Mouse mAb diluted at 1:2000.

  •  Immunohistochemical analysis of paraffin-embedded Human Prostate Tissue using P63-α(EM1404)Mouse mAb diluted at 1:200.

  •  Immunohistochemical analysis of paraffin-embedded Human Prostate Tissue using P63-α(EM1404)Mouse mAb diluted at 1:200.