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ATG5 (3C7) Mouse mAb

Catalog No. : EM1374

Specification Price
50µl $148
100µl $248

Overview

Product name: ATG5 (3C7) Mouse mAb
Source: Mouse
Applications: WB, IHC
Species reactivity: Human,Mouse,Rat
Recommended dilutions: WB  1:5,000-10,000 IHC 1:100-200
Immunogen: Recombinant Protein
Specificity: Human
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/ml
Observed band: 55kDa
GeneID(Human): 9494
Human Swiss-Prot No.: Q9H1Y0
Cellular localization: Cytoplasm, Membrane
Alternative Names: APG5, APG5L, ASP, Autophagy protein 5 antibody
Background: Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.
  • Immunohistochemical analysis of paraffin-embedded Human Ovarian Carcinoma Tissue using ATG5 (EM1374)Mouse mAb diluted at 1:200.

  • Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using ATG5 (EM1374)Mouse mAb diluted at 1:200. 

  •  Western blot analysis of Hela Cell Lysate using ATG5 (EM1374)Mouse mAb diluted at 1:10000.